Compound
TB-500Branded as THROTTLE-500
MGMT RESEARCHPRODUCT CONCEPT
REGENERATIVE & REPAIR RESEARCH
THROTTLE-500 10 mg
TB-500 · Synthetic thymosin beta-4 fragment
TB-500, a synthetic version of thymosin beta-4, accelerates injury recovery, reduces inflammation, promotes new blood vessel formation, enhances tissue repair, and improves flexibility and endurance by regulating actin polymerization and cell migration, making it a go-to peptide for athletes, injury rehab, and performance optimization.
$70.00 CADPer vial · 10 mg
01 / COMPOUND PROFILESynthetic thymosin beta-4 fragment
02 / QUALITYCOA pending
03 / FULFILLMENTToronto dispatch
04 / FORMATLyophilized powder
Category
Regenerative & RepairPeptide research
Vial quantity
10 mgSingle vial option
Research focus
Actin dynamicsCell migration and tissue repair
Product format
Lyophilized powder10 mg labelled vial
Batch testing
COA pendingSideChain Analytics · Mississauga, Ontario
DESCRIPTION
What is THROTTLE-500 10 mg?
THROTTLE-500 is our name for TB-500.
TB-500 is a synthetic fragment (typically the N-terminal 7-17 amino acids, often Ac-LKKTETQ) of thymosin beta-4 (Tβ4), a naturally occurring 43-amino-acid peptide abundant in most mammalian cells.
Each vial contains 10 mg of labelled lyophilized compound.
MECHANISM / RESEARCH INTERESTActin dynamics.
Actin dynamics.
Tissue repair.
Its primary mechanism involves binding to monomeric G-actin, sequestering it in a 1:1 complex to act as an actin buffer: this prevents unwanted polymerization into F-actin filaments while maintaining a readily available pool of G-actin monomers for rapid cytoskeletal remodeling when needed.
By modulating actin dynamics, TB-500 promotes cell migration (chemotaxis and haptotaxis), cytoskeletal reorganization, and motility of key repair cells like fibroblasts, endothelial cells, keratinocytes, and stem/progenitor cells.
It also drives angiogenesis through upregulation of VEGF and other factors, endothelial cell migration/proliferation, and capillary-like structure formation, improving blood supply to damaged tissues.
Additional effects include reduced inflammation (via downregulation of cytokines/chemokines and NF-κB/Toll-like receptor pathways), decreased apoptosis (cytoprotection, increased BCL-2, reduced cytochrome c release), inhibition of excessive scar formation/fibrosis (fewer myofibroblasts), and enhanced extracellular matrix remodeling (via metalloproteinases).
These actions collectively accelerate wound healing, tissue regeneration, and repair in muscles, tendons, ligaments, skin, cornea, heart, and other systems in preclinical models, with effects observed across multiple organs without directly mimicking full-length Tβ4’s broader gene regulation.
Product specifications & handling +
- Product
- THROTTLE-500 · TB-500
- Vial quantity
- 10 mg
- Form
- Lyophilized powder
- Testing
- COA pending · SideChain Analytics
Follow batch-specific supplier instructions and your laboratory’s validated storage and reconstitution procedures.
COA pending. Purity and net-content results will be published when the batch-specific report is available.
MIX EASYYour mixture.
Your mixture.
Made clear.
Select your compound, vial amount, diluent volume, and sample amount. Our calculator converts your inputs into a concentration, volume, and U-100 syringe marking.
01
Set your mixture
mg
mL
Enter an example amount to calculate its volume.
02
Your measurement
THROTTLE-500
20units
0.2 mL of solution per sample
U-100 scale1 mL = 100 units
Concentration10 mg/mL
Full samples per vial5
THE CALCULATION
2 mg ÷ 10 mg/mL = 0.2 mL
How to read this calculator +
Concentration = vial amount ÷ solution volume. Sample volume = sample amount ÷ concentration. U-100 scale units = volume in mL × 100; these are volume markings, not units of compound potency.
This example assumes the final solution volume equals the diluent volume entered, and that the compound dissolves completely. It does not establish solubility, compatibility, stability, or an administration dose.
Decimal measurements are mathematical results and may fall between markings. Full samples are rounded down; they do not account for handling losses.
The calculator checks concentration mathematics. It does not select a treatment dose or establish compatibility, sterility, or stability. SEMARO is temporarily unavailable and is omitted from this selector. BAC Water is the diluent, not a peptide.
SIDE EFFECTS & CONSIDERATIONS
Research considerations.
Review your laboratory’s approved protocol, supplier documentation, and batch-specific COA before handling THROTTLE-500. The current batch COA is pending.
DOSAGE GUIDELINES / RESEARCH CONTEXT
Vial amount and sample calculations.
The labelled vial amount is 10 mg. Use the Mix Easy calculator with the sample amount specified by your laboratory protocol. The calculator converts your inputs; it does not select a dose.